Total Renew — Advanced Joint & Nerve Relief Cream

22,500+ Happy Customers

4.9/5 (1612+ Reviews)

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Rated 4.9/5 Based on 1612 Reviews

Relief That Doesn't Stop at the Surface.

Deep-penetrating formula

Triple-action technology

Clinically-tested actives

Non-greasy, odor-free

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4.9/5 (1612 Reviews)

Total Renew — Advanced Joint Relief Protocol

Deep-penetrating formula

Triple-action technology

Clinically-tested actives

Non-greasy, odor-free

Free Worldwide Shipping

on orders over $60

90-Day Money Back Guarantee

Satisfaction guaranteed

WARNING: Low Stock Notice

This product sold out 12 times last year. We encourage you to take advantage of the limited sale and buy now. Subscribing protects you against future stock outs.

PS: Only available here, don’t buy fakes on Amazon/eBay

As Seen On:

For three years, I used a walker just to get from the bedroom to the kitchen. Six weeks into Total Renew, I realized the walker was still against the wall — and I'd completely forgotten about it. On my daughter's wedding day, I took her arm and walked her down that aisle without thinking about my knees once.

Robert M., 67

Verified Buyer

For seven years, my husband Hank knelt in front of me every morning to put on my shoes. He never complained. But every time, something inside me broke a little. In week five of Total Renew, I bent down and did it myself — no pain, no help. It wasn't about the shoes. It was about my dignity.

Gloria T., 62

Verified Buyer

When arthritis took my fingers, I couldn't hold a screwdriver or button my own shirt. After seven weeks of applying Total Renew, I sat at my workbench and repaired two watches in the same week. My hands are back. And honestly, so am I.

Arthur B., 73

Verified Buyer

I used to make excuses every time Sophie asked me to play outside. I had a knee replacement scheduled and I was terrified. Six weeks into Total Renew, I canceled the surgery. Eight weeks in, I pushed her on those swings until my arms got tired — not my knees.

Linda W., 68

Verified Buyer

Clinically-Studied Ingredients

Backed by 100+ Studies on Joint Comfort and Mobility

Designed to Address What Most Creams Miss

Most joint creams mute the sensation for an hour or two — but the underlying activity keeps going. Studies on enzymes like MMPs suggest these may play a role in how cartilage changes over time. That's why Total Renew was formulated around ingredients researchers have explored for their potential to support a calmer joint environment. Not a quick distraction. Real, daily support.

Supports That Smooth, Lubricated Feeling

Long-term inflammation is associated with depletion of the natural fluids that keep joints feeling smooth. Total Renew is formulated with low-molecular-weight Hyaluronic Acid — designed to be absorbed where standard hyaluronic acid never reaches. Less grinding. More glide. The way it should be.

Reaches the Joint Area From the Outside In

Standard creams stop at the surface. Total Renew uses a deep-penetrating delivery system formulated to carry clinically-studied compounds through the skin and into the joint area — no detour through the stomach, no absorption loss. Straight to where the support is wanted.

A Protocol That Lasts Beyond the Bottle

The full 6-month protocol gives your routine the time it needs — not a 20-minute distraction. Most customers find that once they finish it, a simple maintenance routine keeps them feeling great. The comfort you build is real. And it doesn't disappear when you stop.

Nature’s Best in Balance

Pure and natural ingredients:

Melittin (Bee Venom Extract)

The cornerstone of the formula. Research from Washington University in St. Louis explored how Melittin, applied topically, penetrates through the skin to reach joint tissue — where studies have examined its potential interaction with the inflammatory signaling associated with cartilage-related enzymes (MMPs). Most companies won't touch it because it's expensive and difficult to source. We built our entire formula around it.

Boswellia Serrata

Featured in research published in the Indian Journal of Pharmaceutical Sciences, Boswellia has been studied for its interaction with the same inflammatory pathways researchers associate with joint discomfort. It works alongside Melittin to support a calm, comfortable feeling around the joint area.

Hyaluronic Acid

Standard hyaluronic acid sits on the skin's surface and never reaches the joint area. The low-molecular-weight version we use is small enough to actually penetrate where it can do the most good — designed to support the natural fluid environment around the joint. Less grinding. More glide.

Apigenin (from Chamomile)

A flavonoid naturally found in chamomile that researchers have studied for its interaction with MMP-3 and MMP-13 — enzymes the body produces during periods of joint inflammation. A clinical paper from the University of Medical Sciences in Shiraz documented meaningful comfort improvements and better mobility with topical chamomile use on stiff knees.

Type II Collagen

Formulated at a molecular weight specifically designed to be absorbed through the skin. Clinical research at Harvard Medical School has explored this form of collagen and how the body's signaling responds to it — a key reason it's part of our long-term protocol.